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Should you be fitting a family of datasets together using global nonlinear regression? Why does Prism say "unstable" rather than reporting a best-fit value?.Should you be constraining a parameter (or several) to constant values? If not, should you be constraining them to have a range of values (only positive numbers, perhaps)?.Does your data actually define all the parameters?.If a value doesn't make any sense, ask your self these questions: What if a parameter value makes no biological or chemical sense? Next, make sure each value makes biological or scientific sense. First make sure you know what units each parameter is expressed in (if there are any units some parameters are unitless constants). Exploring these files will help you master graphing with Prism.Before trying to interpret the rest of the results, first look at the best-fit value of each parameter in your model.

Many of these portfolio graphs are linked to step-by-step instructions. When you open a portfolio graph, you'll see a brief explanation of how that graph was made, and can explore the details. Global nonlinear regression (dose-response curves)Ĭhoose the Portfolio tab at the bottom of the Welcome (File.New) dialog to browse dozens of polished graphs, each of which demonstrates several Prism features. Each sample data set comes with brief instructions, and links to longer explanations.Īutomatic outlier elimination (exponential decay) After choosing one of the eight kinds of tables, choose "Start with sample data to follow a tutorial". Then follow longer detailed tutorials focused on statistical analysis and curve fitting with step-by-step instructions.Ĭhoose these from the Welcome (File.New) dialog. Read this one page tour, which will take about five minutes to follow. They also explain the concepts of data analysis. Both do more than explain how to use Prism.

This Prism Guide is only one of three guides. Browse the Statistics and Regression guides